When it comes to supplementation, timing can be just as important as consistency. That’s especially true with peptide-based supplements, which work best when taken in sync with the body’s natural rhythms. MAKE Wellness offers a range of plant-derived peptide products designed to support energy, recovery, metabolism, focus, hydration, and stress response. Each is taken once per day, but the timing of each one is optimized for specific results.

This sample daily schedule and guide provides a straightforward daily schedule to help you get the most out of each product, whether you’re just starting out or looking to fine-tune your current routine.
LEAN: First Thing in the Morning, Before Food
LEAN is designed to support fat metabolism and metabolic function throughout the day. For best results, it can be taken first thing in the morning on an empty stomach. This allows the peptide blend to begin working before food intake and digestion begin, which may enhance its ability to support key metabolic signals. Taking LEAN prior to breakfast helps align its effects with the body’s natural energy production cycle.
FIT: Morning, Before or After Movement
FIT supports strength, movement, and recovery, making it an ideal supplement to take during the morning hours. It can be used either before physical activity to prime the body or afterward to aid in recovery. While it pairs well with workout days, it is also useful on days when general movement or physical exertion is expected. Taking FIT in the morning helps ensure that its benefits align with the times of day when the body is most active.

HYDRATED: Any Time of Day
HYDRATED is the most flexible product in the lineup. It provides electrolytes and minerals to support hydration and can be taken at any time of day. Many people prefer to take it in the morning to rehydrate after sleep, but it is equally effective mid-day or during periods of physical activity. Whether you’re exercising, feeling run down, or simply looking for a hydration boost, HYDRATED can be used whenever it fits into your routine.
ENERGIZED: Late Morning or Early Afternoon
ENERGIZED offers clean energy support without the crash commonly associated with stimulants. It’s best taken during the late morning or early afternoon, especially when you feel energy levels starting to dip. Since it provides a gentle lift in alertness and performance, it can be especially helpful on busy or mentally demanding days.
FOCUSED: Before Mentally Demanding Tasks
FOCUSED is formulated to support clarity, concentration, and cognitive performance. It can be particularly effective when taken shortly before a mentally demanding task or during the typical afternoon slump. Although it can be taken at various times, many users find the most benefit when using it mid-day to enhance productivity and mental stamina. Unlike stimulant-based focus aids, FOCUSED works more subtly and doesn’t interfere with sleep when taken in the afternoon.
CALM: Evening or During Periods of Stress
CALM is designed to support the nervous system and promote a sense of calm and balance without causing drowsiness. It is best taken in the evening as part of a wind-down routine or at any point during the day when stress or tension is high. Because it is non-sedating, it won’t interfere with daytime alertness, making it a useful tool for both evening relaxation and mid-day emotional support.

Final Thoughts
Each MAKE Wellness product is designed to work in harmony with the body, but when you take them can make a significant difference. By aligning supplementation with your body’s natural cycles—such as energy peaks, mental focus windows, and recovery periods—you can enhance the effectiveness of each product.
Building a consistent daily rhythm also makes it easier to stick with a routine, and the once-daily dosing for each supplement keeps things simple. If you’re new to peptides or looking to personalize your wellness schedule, this guide provides a useful starting point.
For more information on the benefits of plant-based peptides or to explore each product in more detail, visit the Peptide Library or browse the full product lineup at MAKE Wellness.
These statements have not been evaluated by the Food and Drug Administration. The contents of this article, made available via Holistic Fit LLC, are for informational purposes only and do not constitute medical advice. The Content presented here is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition. If you think you may be suffering from any medical condition, you should seek immediate medical attention. You should never delay seeking medical advice, disregard medical advice, or discontinue medical treatment because of information provided by Holistic Fit LLC. Reliance on any information provided by this article is solely at your own risk. The author is not a licensed medical professional. References to specific products, research, or external websites are for informational purposes only and do not constitute endorsements or recommendations. Individual results may vary. Readers are encouraged to consult updated sources and verify information as scientific knowledge evolves. And, of course, never use a new product, herb or essential oil without first reading the label, doing your research, or checking with a local expert.
Trina Krug is a Holistic Nutritionist, Integrative Health Coach and host of the Carbless Conversations Podcast. With a Master’s Degree in Complementary and Alternative Medicine, her single mission in life is to facilitate self-healing in herself and those around her through awareness, lifestyle shifts and low-carb eating. As a current Doctor of Science student, she continues her studies in functional nutrition.